Abstract 13606: Is Pulmonary Hypertension a Poor Prognostic Sign in Patients Hospitalized for Transcatheter Aortic Valve Replacement

Autor: Mohsin S Mughal, Ali Ghani, Sundeep Kumar, Ammar Nasir, Hamza Hafeez, Jagpreet Grewal, Talha Ahmad, Sara Aslam, Hafsa Akbar, Muhammad Khakwani, Mahboob Alam, najam wasty, Sergio Waxman
Rok vydání: 2021
Předmět:
Zdroj: Circulation. 144
ISSN: 1524-4539
0009-7322
Popis: Introduction: Pulmonary hypertension (PH) is common in patients with severe aortic stenosis (AS). The prevalence of PH in transcatheter aortic valve replacement (TAVR) patients is reported upto 78% and causes significant morbidity and mortality. We queried the National Inpatient Sample (NIS) database to explore the different outcomes of patients hospitalized for TAVR with and without the history of PH. Hypothesis: PH may increase mortality in hospitalized patients undergoing TAVR. Methods: This is a retrospective cohort study utilizing the 2016-2017 National Inpatient Sample. We identified patients hospitalized for TAVR with and without the history of PH using ICD10 codes. The primary outcome was inpatient mortality. The secondary outcomes were cost of hospitalization, and length of stay (LOS). Multivariate regression was used to adjust for potential confounders including age, gender, race, pulmonary embolism, acute coronary syndrome, heart block, left bundle branch block (LBBB), diabetes, heart failure, and chronic kidney disease. STATA 15.0 was utilized for data analysis. Results: A total of 18221 patients underwent TAVR in 2016-2017. Of these, 18.3% had PH. There were more women in the PH group (51% vs 46%, P Conclusions: Our study showed higher inpatient mortality, length of stay, and cost of hospitalization in patients undergoing TAVR with PH as compared to those without PH.
Databáze: OpenAIRE