Engineering T Cell Receptors for Optimal Affinities and Desired Specificities

Autor:	David M. Kranz, Adam S. Chervin, Jennifer D. Stone, Daniel J. Harris, Sheena N. Smith
Rok vydání:	2015
Předmět:	Stereochemistry T-cell receptor chemical and pharmacologic phenomena Biology Major histocompatibility complex Biochemistry Affinities Genetics biology.protein Receptor Molecular Biology Antigenic peptide Intracellular Biotechnology
Zdroj:	The FASEB Journal. 29
ISSN:	1530-6860 0892-6638
DOI:	10.1096/fasebj.29.1_supplement.223.3
Popis:	T cells, via their T-cell receptors (TCRs), evolved to target intracellular antigenic peptides, as cell-surface complexes with MHC products. While the structural and biochemical characteristics of ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2da915aa8751ea45ca201a45d542ca0f https://doi.org/10.1096/fasebj.29.1_supplement.223.3 Zobrazit plný text záznamu Plný text