Mast Cells and Lysozyme Positive Macrophages in Bronchoalveolar Lavage from Patients with Sarcoidosis

Autor: Leif Bjermer, M. Thunell, G. Roos, O. Bäck
Rok vydání: 2009
Předmět:
Zdroj: Acta Medica Scandinavica. 220:161-166
ISSN: 0001-6101
DOI: 10.1111/j.0954-6820.1986.tb02744.x
Popis: In the deteriorating group of sarcoidosis patients, progress towards pulmonary fibrosis is a major problem. In order to benefit from corticosteroids, it is important for the treatment to start early. We studied a group of 45 patients with sarcoidosis. Most of them were newly detected patients and none were under or had currently received corticosteroid therapy. The patients were followed for at least six months. We found that increased amounts of polymorphonuclear neutrophils (PMN) or lysozyme-positive macrophages (Lys+MF) and mast cells (MC) in bronchoalveolar lavage (BAL) could implicate a bad prognosis.
Databáze: OpenAIRE