Drug addiction: a general review of new concepts and future challenges

Autor:	Naseem Akhtar Qureshi, al-Ghamdy Ys, Tariq A. Al-Habeeb
Rok vydání:	2000
Předmět:	medicine.medical_specialty Substance dependence Mechanism (biology) business.industry Addiction media_common.quotation_subject Craving General Medicine Abstinence medicine.disease Psychological dependence Addiction medicine medicine medicine.symptom Psychiatry business media_common
Zdroj:	Eastern Mediterranean Health Journal. 6:723-733
ISSN:	1687-1634 1020-3397
DOI:	10.26719/2000.6.4.723
Popis:	Relevant papers published in peer reviewed journals in the past 2 decades were identified and screened to abstract pertinent information. Substance dependence/addiction, involving both a common brain reward mechanism and longer-lasting molecular and cellular changes, is a preventable chronic, relapsing brain disease and as such a public health problem. Physical and psychological dependence, characterized by withdrawal syndrome, are now given less weight compared with compulsive behaviour and uncontrolled use of drugs in the comprehension of addiction. The challenging components of drug addictions, including counteradaptation, sensitization, abstinence, craving and relapse need further neurobiological and non-neurobiological exploration and understanding, which may be possible through the use of advanced imaging and genetic techniques and animal models of drug addiction together with relevant human studies
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2da427daf453f9f710b49d06f81e77f8 https://doi.org/10.26719/2000.6.4.723 Zobrazit plný text záznamu