Serotonin-immunoreactive Epithelial Cells in the Main Excretory Ducts of Rat Submandibular Glands
| Autor: | Hiroyuki Hayashi, Koji Takahashi, Kazuyoshi Higashi, Osamu Takahashi, Hideko Tsuzuki, Akira Kawata |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
Saliva Pathology biology Medicine (miscellaneous) Chromogranin A Enteroendocrine cell Serotonergic Submandibular gland General Biochemistry Genetics and Molecular Biology Epithelium medicine.anatomical_structure Endocrinology stomatognathic system Excretory system Internal medicine medicine biology.protein General Dentistry Free nerve ending |
| Zdroj: | Journal of Oral Biosciences. 46:20-26 |
| ISSN: | 1349-0079 |
| Popis: | Although several morphological studies of main excretory duct of the submandibular gland have been performed, few reports present immunohistochemical data. Some epithelial cells or basal cells contain dense granules of an array shape by electron microscopic observation. However, the details of granulated cells have not been clarified immunohistochemically. In this study, both protein gene product 9.5 (PGP 9.5) and chromogranin or serotonin immunoreactive cells in the main excretory duct (MED) of the rat submandibular gland were observed. Some nerve endings were also observed among the epithelium of the MED. Therefore, the modifying mechanism of primary saliva in the MED may be regulated by both serotonergic nerve and endocrine cells with serotonin. |
| Databáze: | OpenAIRE |
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