Neural Control of Coughing And Sneezing

Autor: Roger Shannon, Donald C. Boiser, Bruce G. Lindsey
Rok vydání: 2019
Předmět:
Zdroj: Neural Control of the Respiratory Muscles ISBN: 9780429277740
DOI: 10.1201/9780429277740-18
Popis: Coughing and sneezing are protective reflexes that defend the airways against inhaled particles and noxious substances and remove mucus. The central neuronal network mechanisms that process "cough" and "sneeze" receptor inputs and produce the appropriate changes in respiratory muscle activity are poorly understood. Respiratory premotor and motoneurons are concentrated in two regions of the cat medulla. One population is referred to as the dorsal respiratory group (DRG) and corresponds to the ventrolateral nucleus of the solitary tract and the surrounding reticular formation. The second population is called the Botzinger complex/ventral respiratory group (BOT/VRG) and constitutes a longitudinal column of neurons from the rostral to the caudal end of the ventral lateral medulla. Both the DRG and the BOT/VRG also include neurons with only intramedullary projection sites; these cells have various respiratory-modulated discharge patterns and are referred to as propriobulbar.
Databáze: OpenAIRE