Cytology of Primary Pulmonary Meningioma
| Autor: | Yuichi Ishikawa, Junzo Fujiyama, Mayumi Ueno, Takashi Uchiyama, Ieharu Yamazaki, Yukitoshi Satoh |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Pathology
medicine.medical_specialty Histology Lung medicine.diagnostic_test Psammoma body business.industry General Medicine medicine.disease Primary tumor Pathology and Forensic Medicine Meningioma medicine.anatomical_structure Cytopathology Cytology Biopsy medicine Transitional Meningioma business |
| Zdroj: | Acta Cytologica. 42:1424-1430 |
| ISSN: | 1938-2650 0001-5547 |
| Popis: | Background Ectopic meningiomas arising in the lung are rare. We report here the first multiple primary case diagnosed by intraoperative imprint cytology. Case Asymptomatic pulmonary nodules, two in the left and three in the right lung, were found in a 61-year-old woman, and video-assisted thoracoscopic surgery was undertaken. Because the largest tumor was diagnosed as a meningioma by intraoperative imprint cytology using an excised biopsy specimen, further resection was not performed immediately. Histopathologically the tumor was characterized by whorled nests of cells accompanied by psammoma bodies intermingled with a fibrous pattern. The diagnosis was a transitional meningioma, positive for vimentin and epithelial membrane antigen and negative for keratin immunohistochemically. All the nodules were subsequently surgically resected and showed a similar cytohistologic appearance. Ultrastructurally the tumor cells demonstrated interdigitation of adjacent plasma membranes with numerous desmosomes and hemidesmosomes, typical of meningiomas. We failed to detect another primary tumor in the nervous system, and at this writing the patient was healthy three years after the operation. Conclusion Because of the characteristic cytomorphologic features of primary pulmonary meningioma, the cytologic approach provides useful information for therapy. |
| Databáze: | OpenAIRE |
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