| Popis: |
Multifunctional therapeutic nanocarriers have a significant impact in today’s biomedical and pharmaceutical applications to develop personalized nanomedicines. Especially, polymeric therapeutic nanoparticles have great interest due to their controllable size, shape, surface chemistry properties and their biodegradability, biocompatibility, nontoxicity, prolonged circulation time, tissue penetration, and bioimaging properties for preclinical therapeutic applications. Unfortunately, there does not exist yet an effective and commercial polymeric nanocarriers in clinical trials, because the human body has many challenges such as toxicity, biological barriers, biodistribution, targeted cellular uptake, and so forth. Polymeric nanocarriers need to overcome these limitations to be able to exhibit an efficient therapeutic property. For this purpose, researchers are trying to develop new nanoparticle systems that might overcome these limitations. In this chapter, we will discuss the challenges and future prospects of polymeric nanoparticles which are used in clinical applications for both bioimaging and treatment. |
