| Autor: |
Jana L Jacobs, Ghady Haidar, Asma Naqvi, Kevin D McCormick, Michele Sobolewski, Benjamin R Treat, Amy L Heaps, Jordan Simpson, Kailey Hughes Kramer, Erin McCreary, J Ryan Bariola, Cynthia Klamar-Blain, Bernard J C Macatangay, Dimiter Dimitrov, Wei Li, Christopher C Marino, Anastasios Raptis, Rahil Sethi, Uma Chandran, Simon Barratt-Boyes, Urvi M Parikh, John W Mellors |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Open Forum Infectious Diseases. 10 |
| ISSN: |
2328-8957 |
| Popis: |
Prolonged coronavirus disease 2019 may generate new viral variants. We report an immunocompromised patient treated with monoclonal antibodies who experienced rebound of viral RNA and emergence of an antibody-resistant (>1000-fold) variant containing 5 mutations in the spike gene. The mutant virus was isolated from respiratory secretions, suggesting the potential for secondary transmission. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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