The Self-Assembly of Diblock Copolymers MePEG-b-PAAm into Micellar Structures and Their Interaction with Doxorubicin

Autor: L. R. Kunitskaya, Alexander D. Roshal, V. A. Aleinichenko, Tatyana Zheltonozhskaya, I. K. Khayetsky
Rok vydání: 2011
Předmět:
Zdroj: Molecular Crystals and Liquid Crystals. 536:166/[398]-172/[404]
ISSN: 1563-5287
1542-1406
DOI: 10.1080/15421406.2011.538603
Popis: The micellization of asymmetric diblock copolymers (DBC) MePEG-b-PAAm formed by monomethoxy-poly(ethylene)oxide (MePEG) and polyacrylamide (PAAm) has been studied in water, a water/alcohol mixture, and a NaCl solution. The effect of added NaCl on the critical micellization concentration of DBC water solutions was examined. The interaction between DBC and antitumor drug doxorubicin is discussed. The analysis of the UV spectrum of doxorubicin is performed.
Databáze: OpenAIRE