| Autor: |
W. M. Baarends, Jos W. Hoogerbrugge, H. P. Roest, P. J. M. Hendriksen, J. A. Grootegoed, J.H.J. Hoeijmakers |
| Rok vydání: |
1998 |
| Předmět: |
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| Zdroj: |
Testicular Function: From Gene Expression to Genetic Manipulation ISBN: 9783662036730 |
| DOI: |
10.1007/978-3-662-03671-6_5 |
| Popis: |
The developmental series of events during spermatogenesis that leads to the enclosure of a haploid genome in the head of the highly specialized spermatozoon requires strict control of gene expression (Grootegoed 1996). This control of gene expression shows different properties during the mitotic, meiotic, and postmeiotic phases of spermatogenesis. However, these phases form a continuum. This is most evident for the transition of meiotic spermatocytes into postmeiotic spermatids, since spermatocytes already express a number of genes which encode proteins that are essential for sperm function rather than for meiotic events. Spermatogonia may have a similar foresight. The mitotic step from B spermatogonia to preleptotene primary spermatocytes is often considered as the point of entry into meiosis, but it should be noted that A1 spermatogonia already have embarked on a one-way pathway leading to the meiotic prophase. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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