Seminal plasma lipid peroxidation, total antioxidant capacity, and cigarette smoking in asthenoteratospermic men
| Autor: | Abasalt Hosseinzadeh Colagar, Maryam Gholinezhad Chari |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Antioxidant business.industry Urology medicine.medical_treatment Motility Semen General Medicine medicine.disease Malondialdehyde medicine.disease_cause Lipid peroxidation chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine TBARS business Cell damage Oxidative stress |
| Zdroj: | Journal of Men's Health. 8:43-49 |
| ISSN: | 1875-6867 |
| Popis: | Background: Lipid peroxidation (LPO) is one of the most important effects of ROS-induced cell damage that, along with the formation of reactive and mutagenic aldehyde products such as malondialdehyde (MDA), leads to defective functions in spermatozoa. Total antioxidant capacity (TAC) in the seminal plasma neutralizes ROS so they could be a defense system against LPO. We evaluated the effect of seminal LPO and TAC on the motility and morphology of spermatozoa. We also determined the relationship between cigarette smoking as an exogenous source of ROS in increased levels of MDA and decreased TAC to estimate the intensity of oxidative stress. Methods: MDA concentration and the TAC levels of seminal plasma were measured in asthenoteratospermic cigarette smokers (n = 15), asthenoteratospermic non-smokers (n = 17) and healthy non-smokers (n = 13) using the TBARs and FRAP methods, respectively. Results: The mean TAC in the seminal plasma of healthy men was significantly higher than that in asthenoterato... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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