Synthesis of 6-methyl-8H-dibenzo[a,g]quinolizin-8-imines via Reissert compounds

Autor: Jürgen Krauss, Eberhard Reimann, Rainer Hertel
Rok vydání: 2008
Předmět:
Zdroj: Monatshefte für Chemie - Chemical Monthly. 139:673-684
ISSN: 1434-4475
0026-9247
DOI: 10.1007/s00706-007-0826-8
Popis: Alkylation of Reissert compounds derived from 3-methylisoquinolines with several 2-cyanobenzylbromides followed by hydrolytic cleavage provided the corresponding 1-benzyl-3-methylisoquinolines. Treatment of the latter with methylmagnesiumiodide caused cyclization to the title compounds rather than formation of 2-acetylbenzylisoquinolines.
Databáze: OpenAIRE
Externí odkaz: