Visible-light photoredox-catalyzed coupling of alkylsulfones with α-(trifluoromethyl)styrenes

Autor:	Yasuyo Tahara, Koushik Ghosh, Masakazu Nambo
Rok vydání:	2023
Předmět:	Organic Chemistry General Chemistry Catalysis
Zdroj:	Canadian Journal of Chemistry.
ISSN:	1480-3291 0008-4042
DOI:	10.1139/cjc-2022-0271
Popis:	The synthesis of gem-difluoroalkenes by photocatalytic desulfonylative coupling of alkylsulfones with α-(trifluoromethyl)styrenes is described. Photoredox Ir complex was found to be an effective catalyst for this transformation through single electron reduction of alkyl 1-phenyltetrazolyl sulfones, providing structurally diverse gem-difluoroalkene products in good yields. The resulting alkenes could be further converted into fluorinated derivatives, highlighting the potential utility of this method in the synthesis of organofluorine compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2d0afd734a1fc099f450adfacfb61f75 https://doi.org/10.1139/cjc-2022-0271 Zobrazit plný text záznamu