| Popis: |
Introduction: We aimed to evaluate cardiovascular risks and influencing factors by measuring aortic elasticity parameters and carotid intima thickness in children with cronic renal failure (CRF), and also evaluated the hydration status of patients with Bioimpedance spectroscopy (BIS) measurements and investigated the effect of hydration status on vascular functions. Metods: The study group consisted of 38 patients with CRF, their ages between 6 to 20 years (mean ± SD= 13.34 ± 3.74), of which 16 were girls and 22 were boys. The control group, which consisted of 31 healthy children between 7 and 16.5 years of age (mean ± SD= 12.1± 2.92), 16 girls and 15 boys). Left ventricular end-diastolic, end-systolic, left atrial diameters, interventricular septum, and left ventricular posterior wall thickness were measured. Systolic and diastolic diameters of the aortic annulus and aorta at each level were obtained; z-scores, aortic strain, distensibility, stiffness index were calculated. Carotid intima-media thickness and flow- mediated dilatation were studied. Bioimpedance spectroscopy was performed to all patients. Results: Interventricular septum and left atrial (p=0,002, p=0,013), sinus valsalva and sinotubular junction z scores (p=0,009, p=0,012) were found to be higher and distensibility and strain decreased, stiffness index increased in the abdominal aorta of patients with CRF (p=0,007, p=0,002, p=0,004). Patients with CRF had statistically significant over-hydration. Conclusion: Vascular wall changes that affect the elastic properties of the aortic wall begin to develop in childhood in patients with CRF. This is related to the severity of the disease and the patient’s hydration status. |
