A Comprehensive Review of Three-Dimensional Neuro-Organoids and Engineering Brain-on-a-Chip Microfluidic Devices
Autor: | Nandan Shettigar, Lamees I. El Nihum, Debjyoti Banerjee, Robert Krencik |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Volume 3: Fluid Mechanics; Micro and Nano Fluid Dynamics; Multiphase Flow. |
DOI: | 10.1115/fedsm2021-65892 |
Popis: | The focus of this review is to describe advances in three-dimensional (3D) organoids reported in the literature with an emphasis on the engineering of microfluidic device platforms for investigating neuro-organoids. Furthermore, the paper will assess current limitations in microfluidic design that must be addressed for realizing the full potential of brain-on-a-chip devices. |
Databáze: | OpenAIRE |
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