Phytotoxic Neocassane Diterpenes from Eragrostis plana
| Autor: | Andrea N. L. Batista, Francisco A. Marques, Sirlei Dias Teixeira, Ana Paula P K Hendges, Vanderlei Aparecido de Lima, Beatriz Helena L. N. Sales Maia, João M. Batista, Michelangelo Muzell Trezzi, Francielli S. Santana, Elaine Fernanda Dos Santos |
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| Rok vydání: | 2020 |
| Předmět: |
Pharmacology
Ipomoea grandifolia biology Chemistry Organic Chemistry Pharmaceutical Science Euphorbia heterophylla biology.organism_classification Analytical Chemistry Horticulture Complementary and alternative medicine Eragrostis plana Germination Drug Discovery Vibrational circular dichroism Herbicide glyphosate Radicle Molecular Medicine |
| Zdroj: | Journal of Natural Products. 83:3511-3518 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/acs.jnatprod.0c00324 |
| Popis: | Five new neocassane-like diterpenes (1-5) were isolated from the roots of Eragrostis plana. Their structures were elucidated by spectroscopic data, and the absolute configurations of the representative compounds neocassa-12(17),15-dien-3-one (2) and neocassa-12(13),15-diene-3,14-dione (5) were assigned by vibrational circular dichroism. The phytotoxic activity of compounds 3, 4, and 5 was evaluated against the germination and growth of Ipomoea grandifolia and Euphorbia heterophylla. Compound 4 exhibited the most potent activity for growth variables, resulting in the smallest radicle length of I. grandifolia and in the smallest aerial part length of E. heterophylla. Compound 5 reduced the germination speed index more effectively than the herbicide glyphosate (Roundup). |
| Databáze: | OpenAIRE |
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