The study on post-remission therapies in patients with APL after complete remission induced by all-trans retinoic acid

Autor: Xiusong Li, Nianxian Shao, Longan Huang, Jiaxiang Lu, Shurong Chen, Yanhong Li, Jingxiong Xie, Jinwen Yang, Yuchun Ye, Menger Huang, Cuiju Ke, Jingren Chai, Zhuzi Qian, Longjun Gu, Jian Chen, Yuying Zheng, Gualin Sun, Huaiqin Yu, Zhengyi Wang, Ren-rong Ouyang, Fenqin Zhang, Yingmei Zhang
Rok vydání: 1992
Předmět:
Zdroj: Chinese Journal of Cancer Research. 4:58-61
ISSN: 1993-0631
1000-9604
DOI: 10.1007/bf02955003
Popis: As to determine the effect of post-remission therapy in prolonging survival and duration of remission after complete remission, 50 patients with APL in complete remission induced by retinoic acid (RA) were divided into three groups randomly: (A) 30 cases, treated by alternate chemotherapy with RA; (B) 10 cases, with RA alone; (C) 10 cases, only with chemotherapy. The survival curves showed that Group A had the survival time more than 1 year in 87.4%, more than 2 year in 80.7%. 26/30 cases were survival and still in remission, the survival curve tend to be a plateau at 16 months. In Group B more than 1 year in 45.7%. In Group C, more than 1 year in 50%. (Keplan-Meier χ2=8.93P
Databáze: OpenAIRE
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