| Autor: |
Martha Nneoma OFOKANSİ, Ogechukwu N ISİOGUGU, Ikechukwu E PETER, Matthas AGBO, Festus B.c. OKOYE, Peter A AKAH |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Fabad Journal of Pharmaceutical Sciences. |
| ISSN: |
1300-4182 |
| DOI: |
10.55262/fabadeczacilik.1083066 |
| Popis: |
Intracellular pathogens are mainly eliminated by cell-mediated immunity offered by phagocytic cells like neutrophils, macrophages and monocytes. Two tannin glycosides, 1-O-galloyl-6-O-luteoyl-α-D-glucopyranoside (1) and 3-O-methylellagic acid 3'-O-α-rhamnopyranoside (2) were isolated from the ethyl acetate fraction (EF) of the methanol leaf extract of Phyllanthus muellerianus. The structures of the isolated compounds were elucidated by 1H-NMR and by mass spectroscopy. The effects of the isolated compounds on phagocytic competence of macrophages and neutrophils using in vitro models were evaluated. Compounds 1 and 2 significantly (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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