| Popis: |
Metal-acid complexes with tetracycline (TC) and demethylchlortetracycline (DM-CTC) have been evaluated for their ability to increase the levels of antibiotic in the blood of animals, where the acid constituents of the complexes were gluconic acid, various phosphoric acids, or bis-(1-carboxy-1-hydroxyethyl) phosphinic acid. Selected members of these three major groups each have generally resulted in higher blood levels by two of the following three routes of administration: oral, intramuscular, and intravenous. No single group of complexes has produced blood-level enhancement by all three routes. |
Plný text