Synthesis and antibacterial activity of novel arylbis(indol-3-yl)methane derivatives

Autor:	Alexey S Trenin, Elena P. Mirchink, S. N. Lavrenov, Elena B. Isakova, Alexey A. Panov, Alexander M. Korolev
Rok vydání:	2020
Předmět:	0301 basic medicine Pharmacology 010405 organic chemistry Chemistry 030106 microbiology Antimicrobial 01 natural sciences Combinatorial chemistry Methane 0104 chemical sciences 03 medical and health sciences chemistry.chemical_compound Drug Discovery Antibacterial activity
Zdroj:	The Journal of Antibiotics. 74:219-224
ISSN:	1881-1469 0021-8820
Popis:	A series of new compounds—arylbis(indol-3-yl)methylium derivatives—were synthesized and their antimicrobial activity was evaluated. All the compounds turned out to be highly active, with MIC depending on their structure and the length of N-alkyl residues. The parent triarylmethane compounds possess weaker activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2c825d14a87f2aadefd26974072a6159 https://doi.org/10.1038/s41429-020-00389-9 Zobrazit plný text záznamu Full text from SpringerLink