Average and Variation of Oocyte Counts in Women Undergoing in Vitro Fertilization

Autor: Toshihiko Tomiyam a, Keiichi Kumasawa, Nidenori Negoro, Takeshi Taniguchi, Eri Akita
Rok vydání: 2021
Předmět:
Zdroj: Journal of Gynecology and Obstetrics. 9:31
ISSN: 2376-7812
Popis: Artificial reproductive technology (ART) has become a standard treatment for patients with infertility. However the cost is burdensome to infertile patients in some countries. Moreover aging is a critical factor for infertile patients and is accompanied by higher risk of condition and counts of oocytes. In planning ART for a patient, there are two patterns of oocyte pick-up (OPU) method: One is to transfer all the embros which are obtained from one OPU. Then next OPU will be performed when she fails to get pregnant despite using up all embryos. The other method is to repeat several consecutive OPUs until sufficient stock of embryos. The sufficiency depends on age, serum AMH level, etc. This study investigates the deviation in the number of oocytes collected by OPU in infertile patients who received multiple OPU within 1 year. The number of oocytes increased as the average number of oocytes increased. However, the ratio of standard deviation/average decreased. The frequency of required OPU depends on the pregnancy rate per embryo, the background of the patient, and the number of eggs collected at the first or second OPU. Thus, the analysis will reduce their mental and economic burden. Further studies with large-scale data are needed to determine the ideal frequency of OPU.
Databáze: OpenAIRE