Calculations regarding cell metabolism stimulation using photons in the visible wavelength range

Autor: E. E. Scheller, Olaf Minet, Uwe Bindig, Gerhard Müller, E. Rohde
Rok vydání: 2007
Předmět:
Zdroj: Laser Physics Letters. 5:70-74
ISSN: 1612-202X
1612-2011
DOI: 10.1002/lapl.200710087
Popis: The driving force behind the complex system of metabolism is based on the efficient use of potential differences. An intact biological system has a dynamic equilibrium in which the cellular biochemical reactions are in a pseudo-stationary state. The equilibrium can be manipulated by external effects such as, temperature changes brought about radiation absorption. Hot spots can be induced by the absorption of photons in strongly absorbing areas within the tissue or the sub-cellular components. Simulation calculations were carried out and utilized for selective manipulation within a spatially limited target volume, using simplified parameters for observation of the model. A good correlation was established between the results of the simulation and the measuring data based on absorption and scattering values for fibroblasts and liver tissue. Relevant biochemical causes of the stimulation effects at cellular level are considered in the discussion. The effect of stimulation with a laser on tissue such as cartilage, using a simplified two-dimensional tissue model system which is mainly supplied by diffusion processes, is discussed here with a view to its use in medicine.
Databáze: OpenAIRE
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