Hypophosphatemia and weaning of Mechanically Ventilated patients with Chronic Obstructive Pulmonary Disease during acute exacerbations
| Autor: | Mustafa Mansour Hussien Khalil, Simone Halem Armanious, Galal Adel Abdelrheem Elkad, Ali Ragab Ahmed Adawy |
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| Rok vydání: | 2021 |
| Předmět: |
Mechanical ventilation
medicine.medical_specialty business.industry medicine.medical_treatment Pulmonary disease General Medicine medicine.disease Intensive care unit law.invention law Emergency medicine medicine Weaning Exacerbation acute Prospective cohort study business Hypophosphatemia Cause of death |
| Zdroj: | QJM: An International Journal of Medicine. 114 |
| ISSN: | 1460-2393 1460-2725 |
| DOI: | 10.1093/qjmed/hcab086.013 |
| Popis: | Background Chronic obstructive pulmonary disease (COPD) is a common pulmonary disease. It is currently the third leading cause of death in the United State and is predicted to be the third leading cause of death worldwide by 2020 Objectives The aim of this study is to evaluate the predictive value of serum phosphorus level on weaning of mechanically ventilated chronic obstructive pulmonary disease (COPD) patients with acute exacerbation (AECOPD). Patients and Methods After approval of the medical ethics committee of Faculty of medicine, Ain Shams University, informed consents were taken from the patient’s next of kin to include their data in this study. Results In this prospective cohort study, 116 patients were assessed for enrollment. 26 patients were excluded due to very early mortality at day 1, administration of total parentral nutrition containing phosphorous and very low phosphorus level (less than 1.5 mg/dL or who needs correction). Conclusion In the light of the previous results Hypophosphatemia (1.5 - 2.5 mg/dL) was associated with poor prognosis in terms of longer durations of mechanical ventilations and higher ICU mortality rates in mechanically ventilated patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD), Hypophosphatemia should be included in initial assessment of such patients to stratify them. |
| Databáze: | OpenAIRE |
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