Systemic effect of chitin after intravenous administration to dogs
| Autor: | Yoshiharu Okamoto, T. Sanekata, R. Mura-e, Shin-ichiro Tanioka, Saburo Minami, Akira Matsuhashi, Yoshihiro Shigemasa |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Polymers and Plastics
biology Chemistry fungi Organic Chemistry Fissipedia macromolecular substances Pharmacology Granulocyte biology.organism_classification Oligomer law.invention carbohydrates (lipids) chemistry.chemical_compound medicine.anatomical_structure Chitin law White blood cell Immunology Materials Chemistry medicine Carnivora Physiological saline Chemiluminescence |
| Zdroj: | Carbohydrate Polymers. 33:243-249 |
| ISSN: | 0144-8617 |
| DOI: | 10.1016/s0144-8617(97)00036-2 |
| Popis: | The systemic effect of chitin and chitin oligomer after intravenous administration was investigated in dogs by determining the chemiluminescence (CL) response and the white blood cell count (WBC). Chitin oligomer (2mg/kg) and physiological saline (5ml) did not have a systemic effect. However, in the dogs injected with chitin, WBC decreased significantly from 1 to 4 h after injection and then increased gradually to 1.4 times the pre-injection level at 72 h, while CL was significantly increased 1–2 h after injection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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