| Autor: |
A. Pöpperl, Christian Peters, H. Pöche, Peter Nürnberg, Joachim Hundrieser, Marion Nagy, Joerg Schmidtke, Michael Krawczak, Jochen Hampe, Jörg T. Epplen, J. Kwiatkowska, Ingolf Böhm, Ryszard Słomski |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
DNA Fingerprinting: State of the Science ISBN: 9783764329068 |
| DOI: |
10.1007/978-3-0348-8583-6_22 |
| Popis: |
We report the results of an empirical study of 256 paternity cases referred to 7 different German laboratories for DNA fingerprinting with oligonucleotide probe (CAC)5/(GTG)5. All parameters characteristic of such multilocus DNA fingerprints were found to differ significantly between the contributing centres. Despite these differences, clear-cut decisions between paternity and non-paternity could be made in all but one case. Furthermore, we found no systematic deviation of the gel-phenotype distribution among trios from random expectation as derived from commonly adopted analytical models. Thus, we conclude that oligonucleotide DNA fingerprinting is a robust and reliable means for the resolution of paternity cases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
