A case of multisystem inflammatory syndrome in children in a Japanese boy: with discussion of cytokine profile

Autor: Kei Miyakawa, Mari Iwamoto, Sayaka Fukuda, Takashi Ohya, Mayuko Miyake, Mio Kaneta, Shuichi Ito
Rok vydání: 2021
Předmět:
Zdroj: Modern Rheumatology Case Reports. 5:442-447
ISSN: 2472-5625
DOI: 10.1080/24725625.2021.1920140
Popis: The new disease concept of multisystem inflammatory syndrome in children (MIS-C), which is a systemic inflammatory syndrome with multiple organ involvement after SARS-CoV2 infection, was established in 2020. MIS-C is common in Hispanic and black children in Europe and North America, with few reports in East Asians. A significant portion of patients with MIS-C develop Kawasaki disease (KD)-like symptoms. Therefore, differential diagnosis is challenging, especially in East Asia, where KD is most prevalent. No Japanese cases have been reported in the literatures so far. We report a case of MIS-C in Japan with KD-like symptoms. A 9-year-old Japanese boy, who was infected with SARS-CoV2 1 month previously along with his family, was admitted to our hospital owing to fever for 6 d and erythema mainly in the groyne and pubic area. He also had conjunctivitis, strawberry tongue and diarrhoea. His laboratory findings were as follows: WBC, 12,840/µL (lymphocytes, 4%); CRP, 22.6 mg/dL, pro-calcitonin, 1.8 ng/mL (normal
Databáze: OpenAIRE
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