Modeling the syn-cycle in the light activated opening of the channelrhodopsin-2 ion channel

Autor: Qi Xin, Jie Cheng, Hongwei Wang, Wenying Zhang, Hong Lu, Junpeng Zhou, Glenn V. Lo, Yusheng Dou, Shuai Yuan
Rok vydání: 2022
Předmět:
Zdroj: RSC Advances. 12:6515-6524
ISSN: 2046-2069
Popis: Modelling the syn-cycle is a series of operations on the ChR2 crystal structure (PDB ID: 6EID). By replacement and isomerization, we obtained P500* and P480 intermediates. A feasible explanation that no P390* was observed in experiment was inferred.
Databáze: OpenAIRE