A novel one-pot synthesis of 2-arylpyrazoloquinolinone derivatives
Autor: | Mou Yung Yeh, Chun Hsi Chang, Yun Hwei Shen, Shaw Bing Wen, Ya Lan Wen, Fung Fuh Wong, En Chiuan Chang |
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Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Tetrahedron. 68:5920-5924 |
ISSN: | 0040-4020 |
Popis: | Two regioisomers of 2-arylpyrazolo[3,4-c]quinolin-4(5H)-ones and 2-arylpyrazolo[4,3-c]quinolin-4(5H)-ones were synthesized by utilizing 3-arylsydnones, ethyl 3-bromopropynoate, and 2-aminophenylboronic acid pinacol ester in presence of catalytic agent Pd(PPh3)4. This efficient one-pot synthesis methodology involved 1,3-dipolar cycloaddition, Suzuki coupling reaction, and intramolecular cyclization three sequence steps. |
Databáze: | OpenAIRE |
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