A Strategy for the Synthesis of Bicyclic Fused Cyclopentenones from MBH-Carbonates of Propiolaldehydes

Autor:	Chada Raji Reddy, Siddique Z Mohammed, Paridala Kumaraswamy, Roshan Chandrakant Kajare, Amol D. Patil, V. S. Rao Ganga, Andhavaram Ramaraju, Balasubramanian Sridhar
Rok vydání:	2022
Předmět:	Organic Chemistry Catalysis
Zdroj:	Synthesis. 54:3623-3630
ISSN:	1437-210X 0039-7881
DOI:	10.1055/a-1828-1560
Popis:	An effective synthetic approach has been demonstrated for the construction of diverse bicyclic fused cyclopentenones from Morita–Baylis–Hillman (MBH) carbonates of propiolaldehydes. The present transformation was initiated through the propargylation of an alkenylamine with an MBH carbonate followed by the Pauson–Khand reaction of the product methyl 3-(alkenylamino)-2-methylenealk-4-ynoate. This facile method provides diverse scaffolds of cyclopentenone fused with aza-cycles having additional functionality in good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2c1cf72256ae12c9ab3d3c35c1933a3b https://doi.org/10.1055/a-1828-1560 Zobrazit plný text záznamu