Addressing the treatment of macrophage activation syndrome: A challenging balance between immune suppression and infectious risk

Autor: V Vassia, A Iannaccone, S Marengo, A Briozzo, A Brussino, L Alessi, L Brussino, C Norbiato
Rok vydání: 2022
Předmět:
Zdroj: Global Journal of Infectious Diseases and Clinical Research. 8:011-014
ISSN: 2455-5363
Popis: Hemophagocytic Lymphohistiocytosis (HLH) is a rare and potentially life-threatening syndrome related to a dysregulation of cytolytic function of Natural Killer (NK) cells and cytotoxic T cells (CTLs), which in turns leads to an inappropriate immune stimulation and hyperinflammatory state, resulting in hypercytokinemia, accumulation of activated lymphocytes and macrophages [1,2].
Databáze: OpenAIRE