1-O-Hexadecyl-2-Acetyl-SN-3-Glycerophosphoryl- choline (PAF): Some Effects on the Aggregation of Human Platelets by Thrombin or Collagen

Autor:	Edward J. Hornby, Colin R Perry
Rok vydání:	1983
Předmět:	Thrombin Mediator Chemistry Platelet-rich plasma medicine Biophysics lipids (amino acids peptides and proteins) Platelet Hematology respiratory system medicine.drug
Zdroj:	Thrombosis and Haemostasis. 50:586-587
ISSN:	2567-689X 0340-6245
DOI:	10.1055/s-0038-1665261
Popis:	Summary1-O-hexadecyl-2-acetyl-sn-3-glycerophosphorylcholine (PAF) was examined as a potential mediator of aggregation induced by thrombin or high concentrations of collagen in indomethacin treated platelet rich plasma by investigating the response to collagen and thrombin of platelets previously desensitised to PAF. No reduction in the response to collagen or thrombin was observed and it was concluded that PAF was not a mediator of non-prostanoid dependent aggregation in platelets exposed to thrombin or collagen.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2bf0af253df88cbf4f79cd3aaa7894e4 https://doi.org/10.1055/s-0038-1665261 Zobrazit plný text záznamu