Studies on ketene and its derivatives. XCV. Reaction of diketene with acyl azides

Autor:	Tetsuzo Kato, Masayuki Sato, Yuji Suzuki
Rok vydání:	1979
Předmět:	Nitrene Photodissociation Ketene General Chemistry General Medicine Tetramic acid Medicinal chemistry chemistry.chemical_compound chemistry Yield (chemistry) Drug Discovery Organic chemistry Azide Diketene Dichloromethane
Zdroj:	Chemical and Pharmaceutical Bulletin. 27:1181-1185
ISSN:	1347-5223 0009-2363
Popis:	Photolysis of acyl azides (1, 10) in diketene was investigated. Irradiation of a mixture of benzoyl azide (1a) and diketene in dichloromethane gave 1-benzoyl-4-hydroxy-3-pyrrolin-2-one (2a) in 17% yield. Similarly, reaction of diketene with p-anisoyl azide (1b), p-toluoyl azide (1c), p-chlorobenzoyl azide (1d) and ethyl azidoformate (10) gave the corresponding pyrrolinones (2b, 2c, 2d, and 11) in 7-22% yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2bee18f95a79c2ae36fa1afe39f4313a https://doi.org/10.1248/cpb.27.1181 Zobrazit plný text záznamu