Spread of rectal cancer within veins
| Autor: | Sheila Ritchie, B C Morson, Monica Leighton, H. J. R. Bussey, I. C. Talbot, Anthony Owen Hughes |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Poor prognosis
Pathology medicine.medical_specialty 5 year survival rate business.industry Colorectal cancer General Medicine medicine.disease medicine.anatomical_structure cardiovascular system medicine Surgery Clinical significance Stage (cooking) Vein business Prospective cohort study Survival rate |
| Zdroj: | The American Journal of Surgery. 141:15-17 |
| ISSN: | 0002-9610 |
| DOI: | 10.1016/0002-9610(81)90004-0 |
| Popis: | Histologic evidence of venous invasion was demonstrated in 52 percent of 703 cases of rectal carcinoma. Quantitation of venous invasion and follow-up study showed that invasion of extramural veins was associated with a low 5 year survival rate (33 percent), whereas invasion limited to intramural veins was not. Spread into thick-walled extramural veins carries a very poor prognosis (15 of 91 patients survived 5 years). The corrected 5 year survival rate for stage C patients with invasion of thick-walled extramural veins was only 8 percent. Host reactions in and around the walls of invaded veins increase the survival rate; inflammatory damage to the vein walls and endarteritis obliterans are particularly important in this respect. |
| Databáze: | OpenAIRE |
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