A Cyclooligomerisation Approach to Backbone-Modified Cyclic Peptides Bearing Guanidinium Arms

Autor:	Katrina A. Jolliffe, Philip G. Young, Rebecca Y. T. Li, Victoria J. Dungan, Richard J. G Black
Rok vydání:	2009
Předmět:	chemistry.chemical_classification Ester derivatives chemistry.chemical_compound chemistry Stereochemistry Organic Chemistry Side chain Ornithine Cyclic peptide
Zdroj:	Synlett. 2010:551-554
ISSN:	1437-2096 0936-5214
Popis:	Cyclooligomerisation of the pentafluorophenyl ester derivatives of oxazoles, derived from dipeptides containing protected ornithine, diaminobutanoic acid and diaminopropionic acid residues, gives the cyclic trimers as the major products. Deprotection and treatment with guanidinylating agents provides efficient access to backbone rigidified cyclic peptides with guanidinium functionalised side chains.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2bc2ce79b3dd302347d378fa7a74e458 https://doi.org/10.1055/s-0029-1219155 Zobrazit plný text záznamu