Influence of complexation by metal cations on solvophobic retention of crown compounds in reverse-phase high-performance liquid chromatography

Autor:	A. G. Khorti, E. N. Glibin, O.I. Kurenbin, A. D. Ziv, V.V. Nesterov, O. F. Ginzburg, Z. I. Korshunova
Rok vydání:	1991
Předmět:	Chemistry Inorganic chemistry General Chemistry High-performance liquid chromatography Crown Compounds Metal Column chromatography stomatognathic system Stability constants of complexes Phase (matter) visual_art visual_art.visual_art_medium Organic chemistry Solvophobic
Zdroj:	Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 40:1983-1986
ISSN:	1573-9171 0568-5230
DOI:	10.1007/bf00963492
Popis:	The retention of crown compounds in reverse-phase HPLC is determined by their ability to bind to cations present in the eluent. The dependence of the retention of crown compounds on concentration of the binding cation has a break. This enables the stability constant of the crown-compound-cation complex to be calculated. The retention of the antitumor antibiotic actinomycin D in 75% MeOH is demonstrated to depend on [Na+] and not on [K+] for concentrations of the latter from 10−6 to 10−1 M.
Databáze:	OpenAIRE
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