Characteristics and Comorbidities at Start of Tuberculosis Treatment in Three Regions of the Philippines: The St-ATT Cohort

Autor: Anna-Marie Celine Garfin, Julius Patrick Ferrer, Mary Christine Castro, Juan A Solon, Benjamin Faguer, Sharon E. Cox, Mitsuki Koh, Shuichi Suzuki, Naomi R. Saludar, Tansy Edwards, Farzana Ferdous
Rok vydání: 2021
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
Popis: Background: Diabetes and undernutrition are common risk factors for tuberculosis (TB), associated with poor treatment outcomes and exacerbated by TB. Here we describe the characteristics and non-communicable multimorbidity (co-occurrence of 2 or more medical conditions) in Filipino adults at the time of initiating a new TB treatment regimen enrolled into the Starting Anti-TB Treatment (St-ATT) Cohort. Methods and Findings: Nine-hundred participants (69.6% male) were enrolled from 13 public health facilities in Metro Manila (N=184), Negros Occidental (N=372) and Cebu (N=344) within 5 days of starting treatment including 133 (14.8%) initiating the 9 month WHO shorter treatment regimen for multi-drug resistant TB (MDR-TB). Diabetes was defined as HbA1c ≥6.5% and/or current diabetes medication; hypertension as systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg and/or current anti-hypertensive medication, anaemia as haemoglobin
Databáze: OpenAIRE