Radical trans-Hydroboration of Substituted 1,3-Diynes with an N-Heterocyclic Carbene Borane
| Autor: | Tsuyoshi Taniguchi, Kosuke Takahashi, Steven J. Geib, Dennis P. Curran, Katsuhiro Maeda |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Organic Chemistry Borane 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Hydroboration chemistry Thiol Stereoselectivity Physical and Theoretical Chemistry Carbene |
| Zdroj: | Organic Letters. 23:1071-1075 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/acs.orglett.0c04284 |
| Popis: | Monohydroboration of substituted 1,3-diynes with an N-heterocyclic carbene borane (NHC-borane) occurs under radical conditions using an azo initiator, such as ACCN and AIBN, and a thiol as a polarity-reversal catalyst. The reaction is highly regio- and stereoselective and provides stable NHC-(E)-alkynylalkenylboranes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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