Dysplastic Platelets and Circulating Megakaryocytes in Chronic Myeloproliferative Diseases. II. Ultrastructure of Circulating Megakaryocytes

Autor:	Jorge E. Maldonado
Rok vydání:	1974
Předmět:	Chronic myeloproliferative disorders Pathology medicine.medical_specialty business.industry Immunology Ultrastructure Medicine Platelet Cell Biology Hematology Stem cell business Biochemistry
Zdroj:	Blood. 43:811-820
ISSN:	1528-0020 0006-4971
Popis:	Small circulating megakaryocytes were identified in four patients with chronic myeloproliferative disorders, and their morphologic features by light and electron microscopy are described. The morphologic and cytogenetic studies suggest that at least some of these cells are truly mononuclear. The circulating megakaryocytes were associated with the presence of dysplastic platelets. Both findings are thought to represent involvement of the megakaryocytic-platelet line, probably as an expression of stem cell disease.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2b9ce29a90d4565be4ba93868249da76 https://doi.org/10.1182/blood.v43.6.811.811 Zobrazit plný text záznamu