Cholesterol from diet to the retina
| Autor: | Jm Lecerf |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Intermediate-density lipoprotein
Apolipoprotein E medicine.medical_specialty Very low-density lipoprotein biology Cholesterol Reverse cholesterol transport Blood lipids General Medicine Ophthalmology chemistry.chemical_compound Endocrinology chemistry Internal medicine Cholesterylester transfer protein medicine biology.protein lipids (amino acids peptides and proteins) Chylomicron |
| Zdroj: | Acta Ophthalmologica. 89 |
| ISSN: | 1755-3768 1755-375X |
| DOI: | 10.1111/j.1755-3768.2011.2111.x |
| Popis: | Plasma cholesterol is carried in the blood by lipoproteins. Lipoproteins contains lipids (free and esterified cholesterol, triglycerides, and phospholipids, and apolipoproteins). There are in the fasting condition three kinds of lipoproteins : very low-density lipoproteins which are coming from the liver, and contain triglycerides and cholesterol ; low-density lipoproteins which contain mainly cholesterol and apolipoprotein B, and high-density lipoproteins which are involved in the reverse transport of cholesterol. Lipoproteins bring cholesterol to the tissues and cells which use it (gonads and adrenal glands, liver…) and triglycerides which are source of energy for muscle or are stored in adipose tissue The regulation of the plasma lipids metabolism is complex under genetic factors controlling receptors, apolipoprotein synthesis, and other proteins (for transfert, exchanges…). Dietary factors and metabolic factors such as abdominal adiposity may modulate the lipid metabolism. A lot of abnonnalities may affect the level of LDL or HDL cholesterol due to genetic defects, or nutritional diseases. The interpretation of a dyslipidemia often needs a global approach in order to identify the mechanisms, the consequences (cardiovascular risk) and the best treatment with hypolipidemic drugs and/or dietary changes. |
| Databáze: | OpenAIRE |
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