Follow-up of thyroid cancer patients using rhTSH -preliminary results
| Autor: | A. Widjaja, D. Otto, B. Soudah, Börner Ar, M. Hofmann, E. Weckesser, T. Petrich, Hans Kreipe, Wolfram H. Knapp |
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| Rok vydání: | 2001 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases medicine.diagnostic_test business.industry Fdg uptake medicine.medical_treatment Advanced stage Recombinant Human TSH Urology General Medicine Scintigraphy medicine.disease medicine Radiology Nuclear Medicine and imaging Avidity Thyroglobulin business Nuclear medicine Thyroid cancer Hormone |
| Zdroj: | Nuklearmedizin. 40:7-14 |
| ISSN: | 2567-6407 0029-5566 |
| DOI: | 10.1055/s-0038-1623986 |
| Popis: | Summary Aim: In the follow-up of patients with advanced stage thyroid cancer radioiodine scintigraphy, F-l 8-FDG PET and tumormarker hTg using stimulation with recombinant human TSH (rhTSH) were compared to the results of same diagnostic procedures during TSH-suppression or endogenous TSH-stimulation. Methods: 30 patients were investigated in hypothyroidism and after application of rhTSH regarding the serum hormone concentrations, hTg, radioiodine scans and FGD-PET scans. Results: Radioiodine avidity and FDG uptake were significantly higher in 7/30 and 3/5 patients, respectively, compared to endogenous stimulation or TSH-suppression. In about one third of patients hTg increased more than 30%. Conclusion: Our preliminary results indicate a sufficient feasibility and sensitivity of rhTSH not only in the follow-up by hTg and radioiodine scan but also in FDG-PET. |
| Databáze: | OpenAIRE |
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