Interaction of L-Ascorbic Acid with DL-N-Methyl-β-hydroxytryptamine

Autor:	E. I. Lazhko, Ilya I. Rozhkov, Maria N. Preobrazhenskaya, Alexander M. Korolev
Rok vydání:	1998
Předmět:	Acylation Stereochemistry Chemistry Intramolecular force Yield (chemistry) Organic Chemistry Drug Discovery Diastereomer Alkylation Ascorbic acid Biochemistry
Zdroj:	Tetrahedron Letters. 39:109-112
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)10461-0
Popis:	The interaction of DL-N-methyl-β-hydroxytryptamine 1 with L-ascorbic acid 2 proceeds through the 2-C alkylation of 2 and the intramolecular acylation of the methylamino group to yield diastereomeric 3-hydroxy-4-(indol-3-yl)-1-methyl-3-(2,3,4-trihydroxybutyryl)-pyrrolid-2-ones 4a and 5b. © 1997 Elsevier Science Ltd. All rights reserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2b8798e0395dc496bd1822f9b7a0d8da https://doi.org/10.1016/s0040-4039(97)10461-0 Zobrazit plný text záznamu Full Text from ScienceDirect