First total synthesis of (+)-hyacinthacine A2

Autor: Lauriane Rambaud, Philippe Compain, Olivier R. Martin
Rok vydání: 2001
Předmět:
Zdroj: Tetrahedron: Asymmetry. 12:1807-1809
ISSN: 0957-4166
Popis: The first synthesis of (+)-hyacinthacine A 2 has been achieved in six steps from 2,3,5-tri- O -benzyl- d -arabinofuranose in an overall yield of 11%. The structure of this natural product was thus unambiguously established as (1 R, 2 R, 3 R, 7a R )-1,2-dihydroxy-3-hydroxymethylpyrrolizidine.
Databáze: OpenAIRE