First total synthesis of (+)-hyacinthacine A2
Autor: | Lauriane Rambaud, Philippe Compain, Olivier R. Martin |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Tetrahedron: Asymmetry. 12:1807-1809 |
ISSN: | 0957-4166 |
Popis: | The first synthesis of (+)-hyacinthacine A 2 has been achieved in six steps from 2,3,5-tri- O -benzyl- d -arabinofuranose in an overall yield of 11%. The structure of this natural product was thus unambiguously established as (1 R, 2 R, 3 R, 7a R )-1,2-dihydroxy-3-hydroxymethylpyrrolizidine. |
Databáze: | OpenAIRE |
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