Morphological, structural and cytotoxic behavior of starch/silver nanocomposites with synthesized silver nanoparticles using Stevia rebaudiana extracts
| Autor: | Erick A. Juarez-Arellano, Ariana A. Huerta-Heredia, M. A. Peña-Rico, Saúl Sánchez-Valdes, Eduardo Ramírez-Vargas, A.K. Navarro-Mtz, Mario Valera-Zaragoza |
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| Rok vydání: | 2020 |
| Předmět: |
Thermogravimetric analysis
Nanocomposite Polymers and Plastics Starch Nanoparticle 02 engineering and technology General Chemistry engineering.material 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences Silver nanoparticle 0104 chemical sciences chemistry.chemical_compound Stevia rebaudiana Silver chloride chemistry Materials Chemistry engineering Biopolymer 0210 nano-technology Nuclear chemistry |
| Zdroj: | Polymer Bulletin. 78:1683-1701 |
| ISSN: | 1436-2449 0170-0839 |
| Popis: | The synthesis of silver nanoparticles (AgNPs) using a Stevia rebaudiana aqueous extract and their dispersion in starch in order to obtain starch/AgNps nanocomposites are shown in this study. The AgNPs and the starch/AgNPs nanocomposites have been characterized by ultraviolet–visible spectroscopy, optical microscopy, high-resolution transmission electron microscopy, scanning electron microscopy, X-ray diffraction, differential scanning calorimetry and thermogravimetric analysis. Furthermore, the interaction of starch/AgNPs nanocomposites with a MCF-7 breast cancer cell line is analyzed. AgNPs with an average size around 15–20 nm have been obtained. starch/AgNPs nanocomposite morphology changes with the content of silver (3, 5 and 8 mM), from totally separated and dispersed nanoparticles to ribbon-type morphology. The diffraction pattern of the starch/AgNPs-3 nanocomposite indicates the formation of silver chloride nanoparticles (AgClNPs). A cytotoxic behavior of starch/AgNPs-3 nanocomposite on MCF-7 cancer cells with less damage to normal cells is observed. Hence, the high dispersion of the AgNPs or AgClNPs in starch could be influencing the selective cytotoxic behavior. Thus, this study proposes the generation of biocompatible composite materials, with AgNPs immobilized on starch. These materials have selective action against breast cancer cells, where the selectivity is controlled through the AgNPs dispersion on the biopolymer. |
| Databáze: | OpenAIRE |
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