New lignans and diterpenoid glycosides from the fruits of Xanthium italicum Moretti

Autor:	Jing Qu, Yun-Bao Liu, Shi-Shan Yu, Hai-Qiang Wang, Yong Li, Shuang-Gang Ma, Yu-Tong Li, Jiang Fu
Rok vydání:	2021
Předmět:	Pharmacology chemistry.chemical_classification biology Stereochemistry Organic Chemistry Pharmaceutical Science Glycoside General Medicine biology.organism_classification Xanthium Terpenoid Analytical Chemistry Complementary and alternative medicine chemistry Drug Discovery Molecular Medicine
Zdroj:	Journal of Asian Natural Products Research. 24:518-527
ISSN:	1477-2213 1028-6020
DOI:	10.1080/10286020.2021.1938557
Popis:	A pair of new lignans [(+)- 1 and (-)- 1] and three new compounds (2-4), together with a known compound 5, were isolated from the fruits of Xanthium italicum Moretti. The structures of these compounds were determined on the basis of spectroscopic analysis, particularly HR-ESI-MS and 1 D and 2 D NMR. Compounds 2 and 3 showed antinociceptive effects in an acetic acid-induced writhing test in mice with the writhe inhibition rates of 80.50% and 67.89% at the dose of 20 mg/kg, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2b6f9a115cc246f03ec79aa994ab881b https://doi.org/10.1080/10286020.2021.1938557 Zobrazit plný text záznamu