Postoperative Serum C-Reactive Protein and Cerebrospinal Fluid Leakage after Endoscopic Transsphenoidal Surgery
| Autor: | Rei Yamaguchi, Masahiko Tosaka, Naoto Mukada, Haruka Tsuneoka, Hiroya Shimauchi-Otaki, Takaaki Miyagishima, Fumiaki Honda, Yuhei Yoshimoto |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Neurological Surgery Part B: Skull Base. |
| ISSN: | 2193-634X 2193-6331 |
| DOI: | 10.1055/a-1924-9736 |
| Popis: | Objective Postoperative cerebrospinal fluid (CSF) leakage in endoscopic transsphenoidal surgery is a potential risk that requires immediate repair. We investigated the potential of common postoperative hematological examinations for diagnosing postoperative CSF leakage. Methods We retrospectively studied 214 consecutive cases who underwent endoscopic transsphenoidal approach (ETSA; transsellar approach) or extended ETSA (E-ETSA). Patients with postoperative CSF leakage were defined the leak group (group L), and patients without were defined as the nonleak group (group N). Postoperative C-reactive protein (CRP) was compared between the ETSA and E-ETSA groups, and between the N and L groups. Results The values of white blood cell count and CRP 1 to 7 days after surgery were significantly higher in the L group. Especially, CRP was clearly elevated in the L group (p Conclusion Elevated CRP after endoscopic endonasal transsphenoidal surgery is a potential marker of CSF leakage. |
| Databáze: | OpenAIRE |
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