Indole Alkaloids of Haplophyton crooksii
| Autor: | Mohamad A. Mroue, K. L. Euler, M. A. Ghuman, Maktoob Alam |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Pharmacology
Indole test biology Apocynaceae Akuammicine Stereochemistry Alkaloid Organic Chemistry Haplophyton crooksii Pharmaceutical Science Biological activity Pharmacognosy biology.organism_classification Analytical Chemistry Yohimbine chemistry.chemical_compound Complementary and alternative medicine chemistry Drug Discovery medicine Molecular Medicine medicine.drug |
| Zdroj: | Journal of Natural Products. 59:890-893 |
| ISSN: | 1520-6025 0163-3864 |
| Popis: | An investigation of the indole alkaloids of Haplophyton crooksii has resulted in the identification of two new alkaloids10-methoxy-N1-methylpericyclivine (1) and 16-decarbomethoxyvinervinine (2)and 13 known alkaloidscrooksiine, yohimbine, β-yohimbine, crooksidine, decarbomethoxytetrahydrosecodine, akuammicine, tubotaiwine, lanceomigine, lanceomigine N-oxide, haplophytine, cimicine, cimicidine, and akuammidinas major alkaloids of this shrub. All of the isolated alkaloids showed an inhibition of acetylcholinesterase activity in vitro. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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