An Efficient Synthesis of 4-Heterofunction-Substituted 3-(1-Hydroxy)ethylazetidin-2-ones from 3-(1-Hydroxy)ethyl-4-phenylsulfinylazetidin-2-one by Reaction with Silylated Heteronucleophiles

Autor:	Naoki Yoshida, Yasuyuki Kita, Norio Shibata, Takashi Tohjo
Rok vydání:	1992
Předmět:	chemistry.chemical_compound chemistry Drug Discovery Lactam Organic chemistry General Chemistry General Medicine Catalysis
Zdroj:	Chemical and Pharmaceutical Bulletin. 40:1733-1736
ISSN:	1347-5223 0009-2363
DOI:	10.1248/cpb.40.1733
Popis:	3-(1-tert-Butyldimethylsiloxy)ethyl-4-sulfinylazetidin-2-one was reacted with silylated N-, S-, O-, and P-nucleophiles in the presence of a catalytic amount of ZnI2 to give the corresponding trans-4-heterofunction-substituted azetidin-2-ones in high yelids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2b10ab0d73a6cecf732abb7773886ce4 https://doi.org/10.1248/cpb.40.1733 Zobrazit plný text záznamu