Application of 18O-Labeling Method to Structural Analysis of Chondroitin Sulfate Oligosaccharides

Autor:	Shigeyasu Ito
Rok vydání:	2009
Předmět:	chemistry.chemical_classification chemistry.chemical_compound animal structures Chromatography Chemistry Stereochemistry Chondroitin sulfate Oligosaccharide Mass spectrometry Sequence determination
Zdroj:	Journal of the Mass Spectrometry Society of Japan. 57:283-289
ISSN:	1880-4225 1340-8097
DOI:	10.5702/massspec.57.283
Popis:	Numerous studies have been reported on structural analysis of chondroitin sulfate (CS) oligosaccharides using multiple-stage mass spectrometry (MSn). However, their sequence determination is highly complex because of the simply repeating backbone structure. This study attempts to overcome this issue using an 18O-labeling method. The usefulness of the 18O-labeling method in the MSn analysis of CS oligosaccharide is shown in this paper.
Databáze:	OpenAIRE
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