CEQAT-DGHS interlaboratory tests for chemical safety: Validation of laboratory test methods by determining the measurement uncertainty and probability of incorrect classification including so-called 'Shark profiles'
| Autor: | Sabine Zakel, Kirstin Frost, Steffen Uhlig, Peter Lüth, Heike Michael-Schulz, Marcus Malow, Martin Schmidt |
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| Rok vydání: | 2021 |
| Předmět: |
Computer science
business.industry General Chemical Engineering 05 social sciences Energy Engineering and Power Technology 02 engineering and technology Test method Management Science and Operations Research Industrial and Manufacturing Engineering CLP Regulation Reliability engineering 020401 chemical engineering Control and Systems Engineering 0502 economics and business Dangerous goods Measurement uncertainty 050207 economics 0204 chemical engineering Safety Risk Reliability and Quality business Quality assurance Reliability (statistics) Food Science UN Recommendations on the Transport of Dangerous Goods Test data |
| Zdroj: | Journal of Loss Prevention in the Process Industries. 72:104532 |
| ISSN: | 0950-4230 |
| DOI: | 10.1016/j.jlp.2021.104532 |
| Popis: | Laboratory test results are of vital importance for correctly classifying and labelling chemicals as “hazardous” as defined in the UN Globally Harmonized System (GHS)/EC CLP Regulation or as “dangerous goods” as defined in the UN Recommendations on the Transport of Dangerous Goods. Interlaboratory tests play a decisive role in assessing the reliability of laboratory test results. Interlaboratory tests performed over the last 10 years have examined different laboratory test methods. After analysing the results of these interlaboratory tests, the following conclusions can be drawn: 1 There is a need for improvement and validation for all laboratory test methods examined. 2 To avoid any discrepancy concerning the classification and labelling of chemicals, the use of validated laboratory test methods should be state of the art, with the results accompanied by the measurement uncertainty and (if applicable) the probability of incorrect classification. This paper addresses the probability of correct/incorrect classification (for example, as dangerous goods) on the basis of the measurement deviation obtained from interlaboratory tests performed by the Centre for quality assurance for testing of dangerous goods and hazardous substances (CEQAT-DGHS) to validate laboratory test methods. This paper outlines typical results (e.g. so-called “Shark profiles” – the probability of incorrect classification as a function of the true value estimated from interlaboratory test data) as well as general conclusions and steps to be taken to guarantee that laboratory test results are fit for purpose and of high quality. |
| Databáze: | OpenAIRE |
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